Pub. Date : 2008 Jan
PMID : 18085663
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | PAG, the phosphoprotein associated with glycosphingolipid-enriched microdomains (GEM), negatively regulates Src family kinases by recruiting C-terminal Src kinase (Csk) to the membrane, where Csk phosphorylates the inhibitory tyrosine of the Src kinases. | Tyrosine | C-terminal Src kinase | Homo sapiens |
| 2 | The mutant functions by depleting Csk from the GEM fractions, as apparent by changes in the phosphorylation of the inhibitory tyrosines within the Src kinases. | Tyrosine | C-terminal Src kinase | Homo sapiens |