Pub. Date : 2008 Mar
PMID : 18084316
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | KEY RESULTS: Celecoxib (1 nM-10 microM) inhibited, with the same potency, adhesion of HT29 cells to resting HUVEC or to HUVEC stimulated by tumour necrosis factor-alpha (TNF-alpha), mimicking inflammatory conditions. | Celecoxib | tumor necrosis factor | Homo sapiens |
| 2 | Analysis of ICAM-1 and VCAM-1 expression showed that celecoxib inhibited expression of both molecules in TNF-alpha-stimulated HUVEC, but not in resting HUVEC; inhibition was concentration-dependent and maximal (about 50%) at 10 microM celecoxib. | Celecoxib | tumor necrosis factor | Homo sapiens |
| 3 | Analysis of ICAM-1 and VCAM-1 expression showed that celecoxib inhibited expression of both molecules in TNF-alpha-stimulated HUVEC, but not in resting HUVEC; inhibition was concentration-dependent and maximal (about 50%) at 10 microM celecoxib. | Celecoxib | tumor necrosis factor | Homo sapiens |