Pub. Date : 2008 Mar
PMID : 18081741
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Disrupted intracellular calcium regulates BACE1 gene expression via nuclear factor of activated T cells 1 (NFAT 1) signaling. | Calcium | beta-secretase 1 | Homo sapiens |
2 | BACE1 expression was stimulated by a calcium ionophore in primary cortical cultures, and by SH-SY5Y neuroblastoma cells, which was both blocked by pretreatment with either cyclosporin A, an inhibitor of calcineurin, or ethyleneglycotetraacetic acid, a calcium chelator. | Calcium | beta-secretase 1 | Homo sapiens |
3 | BACE1 expression was stimulated by a calcium ionophore in primary cortical cultures, and by SH-SY5Y neuroblastoma cells, which was both blocked by pretreatment with either cyclosporin A, an inhibitor of calcineurin, or ethyleneglycotetraacetic acid, a calcium chelator. | Calcium | beta-secretase 1 | Homo sapiens |