Title : Two modes of ERK activation by TNF in keratinocytes: different cellular outcomes and bi-directional modulation by vitamin D.

Pub. Date : 2008 May 15

PMID : 18080320






2 Functional Relationships(s)
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Protein Name
Organism
1 Pretreatment with calcitriol, enhanced TNF-induced EGFR-Src dependent ERK activation and tyrosine phosphorylation of the EGFR, but abolished the EGFR-Src independent ERK activation. Calcitriol tumor necrosis factor Homo sapiens
2 Treatment with calcitriol increased the rate of the de-phosphorylation of activated ERK, accounting for the inhibition of EGFR-Src independent ERK activation by TNF. Calcitriol tumor necrosis factor Homo sapiens