Pub. Date : 2008 Mar
PMID : 18079363
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Modulation of human multidrug resistance protein (MRP) 1 (ABCC1) and MRP2 (ABCC2) transport activities by endogenous and exogenous glutathione-conjugated catechol metabolites. | Glutathione | ATP binding cassette subfamily C member 1 | Homo sapiens |
| 2 | Modulation of human multidrug resistance protein (MRP) 1 (ABCC1) and MRP2 (ABCC2) transport activities by endogenous and exogenous glutathione-conjugated catechol metabolites. | Glutathione | ATP binding cassette subfamily C member 1 | Homo sapiens |
| 3 | Members of the multidrug resistance protein (MRP/ABCC) subfamily of ATP-binding cassette proteins transport a wide array of anionic compounds, including sulfate, glucuronide, and glutathione (GSH) conjugates. | Glutathione | ATP binding cassette subfamily C member 1 | Homo sapiens |
| 4 | Members of the multidrug resistance protein (MRP/ABCC) subfamily of ATP-binding cassette proteins transport a wide array of anionic compounds, including sulfate, glucuronide, and glutathione (GSH) conjugates. | Glutathione | ATP binding cassette subfamily C member 1 | Homo sapiens |
| 5 | Members of the multidrug resistance protein (MRP/ABCC) subfamily of ATP-binding cassette proteins transport a wide array of anionic compounds, including sulfate, glucuronide, and glutathione (GSH) conjugates. | Glutathione | ATP binding cassette subfamily C member 1 | Homo sapiens |
| 6 | Members of the multidrug resistance protein (MRP/ABCC) subfamily of ATP-binding cassette proteins transport a wide array of anionic compounds, including sulfate, glucuronide, and glutathione (GSH) conjugates. | Glutathione | ATP binding cassette subfamily C member 1 | Homo sapiens |
| 7 | Members of the multidrug resistance protein (MRP/ABCC) subfamily of ATP-binding cassette proteins transport a wide array of anionic compounds, including sulfate, glucuronide, and glutathione (GSH) conjugates. | Glutathione | ATP binding cassette subfamily C member 1 | Homo sapiens |
| 8 | Members of the multidrug resistance protein (MRP/ABCC) subfamily of ATP-binding cassette proteins transport a wide array of anionic compounds, including sulfate, glucuronide, and glutathione (GSH) conjugates. | Glutathione | ATP binding cassette subfamily C member 1 | Homo sapiens |
| 9 | The position of GSH conjugation appears important as all four GS estrogen conjugates tested were potent inhibitors of MRP1 transport, but only the 2-hydroxy-1-(glutathion-S-yl)-estradiol and 2-hydroxy-1-(glutathion-S-yl)-estrone conjugates were potent inhibitors of MRP2-mediated transport. | Glutathione | ATP binding cassette subfamily C member 1 | Homo sapiens |