Title : Investigation of the effect of a panel of model hepatotoxins on the Nrf2-Keap1 defence response pathway in CD-1 mice.

Pub. Date : 2008 Jan 20

PMID : 18078705






1 Functional Relationships(s)
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1 Each compound elicited significant serum ALT increases after 24h (ALT U/L: APAP, 3036+/-1462; BB, 5308+/-2210; CCl4, 5089+/-1665; FS, 2301+/-1053), accompanied by centrilobular damage as assessed by histopathology. Furosemide glutamic pyruvic transaminase, soluble Mus musculus