Title : The tyrosine binding pocket in the adaptor protein 1 (AP-1) mu1 subunit is necessary for Nef to recruit AP-1 to the major histocompatibility complex class I cytoplasmic tail.

Pub. Date : 2008 Feb 8

PMID : 18073204






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Also present in Nef is a dileucine motif, which does not normally affect MHC-I trafficking and is not needed to recruit AP-1 to the Nef-MHC-I-complex. dileucine S100 calcium binding protein B Homo sapiens
2 However, evidence is presented here that this dileucine motif can be activated by fusing Nef to the HLA-A2 tail in cis. dileucine S100 calcium binding protein B Homo sapiens