Title : Assessment of urinary mephenytoin metrics to phenotype for CYP2C19 and CYP2B6 activity.

Pub. Date : 2008 Apr

PMID : 18071681






1 Functional Relationships(s)
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1 RESULTS: Cumulative excretion of 4"-hydroxymephenytoin in urine with beta-glucuronidase treatment collected from before mephenytoin administration up to 12-16 h thereafter showed the greatest difference between CYP2C19 genotypes and the lowest intra-individual variability (7%). Mephenytoin glucuronidase beta Homo sapiens