Title : The effects of a COX-2 inhibitor meloxicam on squamous cell carcinoma of the esophagus in vivo.

Pub. Date : 2008 Apr 1

PMID : 18058818






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1 The effects of a COX-2 inhibitor meloxicam on squamous cell carcinoma of the esophagus in vivo. Meloxicam mitochondrially encoded cytochrome c oxidase II Homo sapiens
2 The purpose of this study was to determine if similar changes occurred in vivo in the tumors of patients with SCC of the esophagus who were given a preferential COX-2 inhibitor, meloxicam. Meloxicam mitochondrially encoded cytochrome c oxidase II Homo sapiens
3 We conclude that meloxicam induces apoptosis in SCC of the esophagus in vivo by inhibiting the pathway of NF-kappaB downstream regulation of COX-2. Meloxicam mitochondrially encoded cytochrome c oxidase II Homo sapiens