Pub. Date : 2008 Feb 15
PMID : 18056705
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In this study, we have found that glucose depletion promotes the phosphorylation of AMP-activated protein kinase catalytic subunit alpha (AMPKalpha) in association with a significant up-regulation of p53, thereby inducing p53-dependent apoptosis in vivo and in vitro. | Glucose | tumor protein p53 | Homo sapiens |
2 | In this study, we have found that glucose depletion promotes the phosphorylation of AMP-activated protein kinase catalytic subunit alpha (AMPKalpha) in association with a significant up-regulation of p53, thereby inducing p53-dependent apoptosis in vivo and in vitro. | Glucose | tumor protein p53 | Homo sapiens |
3 | Small interference RNA-mediated knockdown of p53 caused an inhibition of apoptosis following glucose depletion. | Glucose | tumor protein p53 | Homo sapiens |