Title : Characterization and comparative studies of zebrafish and human recombinant dihydrofolate reductases--inhibition by folic acid and polyphenols.

Pub. Date : 2008 Mar

PMID : 18056255






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Dihydrofolate reductase (DHFR) catalyzes folic acid reduction and recycles dihydrofolate generated during dTMP biosynthesis to tetrahydrofolate. Folic Acid dihydrofolate reductase Danio rerio
2 Dihydrofolate reductase (DHFR) catalyzes folic acid reduction and recycles dihydrofolate generated during dTMP biosynthesis to tetrahydrofolate. Folic Acid dihydrofolate reductase Danio rerio
3 In addition, the DHFR-mediated dihydrofolate reduction was significantly inhibited by its own substrate folic acid. Folic Acid dihydrofolate reductase Danio rerio