Pub. Date : 2008 Mar
PMID : 18055762
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Infrared difference spectra show that concentrations of tetracaine consistent with binding to the ion channel (<50 microM) stabilize a resting-like state when the nAChR is reconstituted into phosphatidylcholine membranes containing the anionic lipid, phosphatidic acid, but have no effect on the nAChR reconstituted into membranes lacking phosphatidic acid, either in the presence or absence of cholesterol. | Tetracaine | cholinergic receptor nicotinic alpha 4 subunit | Homo sapiens |
2 | Infrared difference spectra show that concentrations of tetracaine consistent with binding to the ion channel (<50 microM) stabilize a resting-like state when the nAChR is reconstituted into phosphatidylcholine membranes containing the anionic lipid, phosphatidic acid, but have no effect on the nAChR reconstituted into membranes lacking phosphatidic acid, either in the presence or absence of cholesterol. | Tetracaine | cholinergic receptor nicotinic alpha 4 subunit | Homo sapiens |