Title : Multi-target-directed drug design strategy: from a dual binding site acetylcholinesterase inhibitor to a trifunctional compound against Alzheimer's disease.

Pub. Date : 2007 Dec 27

PMID : 18047264






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The multifunctional compounds show activity against human AChE, are able to inhibit the AChE-induced amyloid-beta aggregation, and chelate metals, such as iron and copper. Copper acetylcholinesterase (Cartwright blood group) Homo sapiens