Title : Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species.

Pub. Date : 2007 Dec 1

PMID : 18032788






1 Functional Relationships(s)
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1 Blocking the expression of autophagic genes (beclin 1 and ATG5) by siRNAs or using the autophagy inhibitor 3-methyladenine (3-MA) decreased cell death that was induced by rotenone or TTFA. 3-methyladenine beclin 1 Homo sapiens