Title : Induction of apoptosis by esculetin in human leukemia U937 cells through activation of JNK and ERK.

Pub. Date : 2008 Mar 1

PMID : 18031783






1 Functional Relationships(s)
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1 Esculetin-induced apoptosis was correlated with mitochondrial dysfunction, leading to the release of cytochrome c from the mitochondria to the cytosol, as well as the proteolytic activation of caspases. esculetin cytochrome c, somatic Homo sapiens