Title : New 1,2,3,4-tetrahydroisoquinoline derivatives as modulators of proteolytic cleavage of amyloid precursor proteins.

Pub. Date : 2008 Feb 15

PMID : 18024043






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1 We investigated the effect of these synthetic tetrahydroisoquinoline derivatives on the regulation of proteolytic processing of amyloid precursor protein (APP) by an ERK-dependent signaling pathway. 1,2,3,4-tetrahydroisoquinoline amyloid beta precursor protein Homo sapiens