Title : 5-Lipoxygenase gene disruption reduces amyloid-beta pathology in a mouse model of Alzheimer's disease.

Pub. Date : 2008 Apr

PMID : 17998412






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 5-Lipoxygenase (5LO), by producing leukotrienes, is a proinflammatory enzyme, and there is evidence suggesting that it is up-regulated with aging and may be involved in Alzheimer"s disease (AD). Leukotrienes arachidonate 5-lipoxygenase Mus musculus