Title : The IQGAP1-Rac1 and IQGAP1-Cdc42 interactions: interfaces differ between the complexes.

Pub. Date : 2008 Jan 18

PMID : 17984089






1 Functional Relationships(s)
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1 Switch II mutations also affect binding to IQGAP1 although the effects differ between Rac1 and Cdc42; mutation of either Asp-63, Arg-68, or Leu-70 abrogate Rac1 binding, whereas no switch II mutations affect Cdc42 binding to IQGAP1. Leucine Rac family small GTPase 1 Homo sapiens