Title : Contributions of phosphorylation to regulation of OCTN2 uptake of carnitine are minimal in BeWo cells.

Pub. Date : 2008 Feb 1

PMID : 17977516






3 Functional Relationships(s)
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Protein Name
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1 Levamisole, an ALP inhibitor, caused a more substantial decrease in carnitine uptake than expected from its corresponding decrease in ALP activity. Carnitine alkaline phosphatase, placental Homo sapiens
2 Levamisole, an ALP inhibitor, caused a more substantial decrease in carnitine uptake than expected from its corresponding decrease in ALP activity. Carnitine alkaline phosphatase, placental Homo sapiens
3 It was determined that levamisole competitively inhibits carnitine uptake, with a K(i) value of 1.01+/-0.05mM, and this effect has a greater role in decreasing carnitine uptake than any indirect effects of ALP inhibition upon OCTN2 function. Carnitine alkaline phosphatase, placental Homo sapiens