Title : Regulation of Na,K-ATPase during acute lung injury.

Pub. Date : 2007 Dec

PMID : 17972021






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Cells exposed to hypoxia generate reactive oxygen species which activate PKC zeta which in turn phosphorylates the Na,K-ATPase at the Ser18 residue in the N-terminus of the alpha1-subunit leading the ubiquitination of any of the four lysines (K16, K17, K19, K20) adjacent to the Ser18 residue. Reactive Oxygen Species keratin 20 Homo sapiens