Title : Sirolimus inhibits human pancreatic carcinoma cell proliferation by a mechanism linked to the targeting of mTOR/HIF-1 alpha/VEGF signaling.

Pub. Date : 2007 Nov

PMID : 17968710






3 Functional Relationships(s)
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1 Sirolimus inhibits human pancreatic carcinoma cell proliferation by a mechanism linked to the targeting of mTOR/HIF-1 alpha/VEGF signaling. Sirolimus hypoxia inducible factor 1 subunit alpha Homo sapiens
2 Sirolimus is effective in vivo against pancreatic carcinoma and demonstrates that the effect of sirolimus on the inhibition of tumor cell proliferation is associated with the suppression of the mTOR/HIF-1alpha/vascular endothelial growth factor (VEGF) pathway. Sirolimus hypoxia inducible factor 1 subunit alpha Homo sapiens
3 Sirolimus is effective in vivo against pancreatic carcinoma and demonstrates that the effect of sirolimus on the inhibition of tumor cell proliferation is associated with the suppression of the mTOR/HIF-1alpha/vascular endothelial growth factor (VEGF) pathway. Sirolimus hypoxia inducible factor 1 subunit alpha Homo sapiens