Pub. Date : 2007 Sep
PMID : 17958324
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Reactive oxygen species mediate ET-1-induced activation of ERK1/2 signaling in cultured feline esophageal smooth muscle cells. | Reactive Oxygen Species | mitogen-activated protein kinase 3 | Homo sapiens |
| 2 | We investigated a possible role for ROS generation in mediating the action of ET-1 on activation of ERK1/2 in cultured feline esophageal smooth muscle cells (ESMC). | Reactive Oxygen Species | mitogen-activated protein kinase 3 | Homo sapiens |
| 3 | Pretreatment of ESMC with N-acetylcysteine, a ROS scavenger, also attenuated the ET-1-induced ERK1/2 activation. | Reactive Oxygen Species | mitogen-activated protein kinase 3 | Homo sapiens |
| 4 | The results suggest that ROS might be critical mediators of the ET-1-induced ERK1/2 signaling events in ESMC. | Reactive Oxygen Species | mitogen-activated protein kinase 3 | Homo sapiens |