Title : Celastrol inhibits polyglutamine aggregation and toxicity though induction of the heat shock response.

Pub. Date : 2007 Dec

PMID : 17943263






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 This effect requires the presence of the transcription factor responsible for mediating inducible hsp gene expression, HSF1, and is correlated with decreased amounts and increased sodium dodecyl sulfate (SDS) solubility of polyglutamine aggregates. polyglutamine heat shock transcription factor 1 Homo sapiens