Pub. Date : 2007 Oct
PMID : 17931083
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | OBJECTIVE: To examine the effect of the I405V and TaqIB polymorphisms of cholesteryl ester transfer protein (CETP) on the lipid response after simvastatin treatment in 180 hypercholesterolaemic patients. | Simvastatin | cholesteryl ester transfer protein | Homo sapiens |
2 | OBJECTIVE: To examine the effect of the I405V and TaqIB polymorphisms of cholesteryl ester transfer protein (CETP) on the lipid response after simvastatin treatment in 180 hypercholesterolaemic patients. | Simvastatin | cholesteryl ester transfer protein | Homo sapiens |
3 | CONCLUSIONS: The authors" findings suggest that CETP I405V polymorphism modifies the effect of simvastatin on TG reduction and HDL-C elevation; the carriers of the I allele responded better to treatment. | Simvastatin | cholesteryl ester transfer protein | Homo sapiens |