Title : (-)Gossypol and its combination with imatinib induce apoptosis in human chronic myeloid leukemic cells.

Pub. Date : 2007 Nov

PMID : 17926190






1 Functional Relationships(s)
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1 Enhanced apoptosis, cytochrome C release, and caspase 3 cleavage as well as noticeable decrease of Mcl-1 and Bcl-XL were observed in K562 cells treated with both (-)gossypol and imatinib. Imatinib Mesylate BCL2 like 1 Homo sapiens