Title : Partial inhibition of integrin alpha(v)beta6 prevents pulmonary fibrosis without exacerbating inflammation.

Pub. Date : 2008 Jan 1

PMID : 17916809






1 Functional Relationships(s)
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1 OBJECTIVES: To analyze the expression of alpha(v)beta6 in human pulmonary fibrosis, and to functionally test the efficacy of therapeutic inhibition of alpha(v)beta6-mediated TGF-beta activation in murine bleomycin-induced pulmonary fibrosis. Bleomycin transforming growth factor beta 1 Homo sapiens