Title : A study on the effects of diclofenac sodium and etoricoxib in the treatment of osteoarthritis.

Pub. Date : 2007 May

PMID : 17915794






3 Functional Relationships(s)
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1 Diclofenac sodium, a non-selective cyclo-oxygenase inhibitor and etoricoxib, a selective cyclo-oxygenase-2 inhibitor have been widely used in treatment of patients with osteo-arthritis. Etoricoxib prostaglandin-endoperoxide synthase 2 Homo sapiens
2 The study shows that etoricoxib provides better clinical efficacy and gastro-intestinal tolerability in osteo-arthritis in comparison to diclofenac sodium presumably due to the selective inhibition of cyclo-oxygenase-2 by etoricoxib. Etoricoxib prostaglandin-endoperoxide synthase 2 Homo sapiens
3 The study shows that etoricoxib provides better clinical efficacy and gastro-intestinal tolerability in osteo-arthritis in comparison to diclofenac sodium presumably due to the selective inhibition of cyclo-oxygenase-2 by etoricoxib. Etoricoxib prostaglandin-endoperoxide synthase 2 Homo sapiens