Pub. Date : 2007 Nov
PMID : 17914575
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A comparison with the wild-type after 1 nano-second molecular dynamic simulation analysis revealed a significant structural change (over 4A displacement) in the contact loop Lys-Ser-Val which lies upstream and next to the mutated site in the TP53, that sterically prevents its DNA-binding activity. | Lysine | tumor protein p53 | Homo sapiens |