Title : Eugenol modulates cyclooxygenase-2 expression through the activation of nuclear factor kappa B in human osteoblasts.

Pub. Date : 2007 Oct

PMID : 17889685






4 Functional Relationships(s)
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1 In addition, COX-2 protein expression in osteoblasts was induced by eugenol in a dose-dependent manner. Eugenol prostaglandin-endoperoxide synthase 2 Homo sapiens
2 Eugenol modulates cyclooxygenase-2 expression through the activation of nuclear factor kappa B in human osteoblasts. Eugenol prostaglandin-endoperoxide synthase 2 Homo sapiens
3 Furthermore, the eugenol-modulated COX-2 expression was inhibited by an NF-kappaB inhibitor, N-acetylcysteine. Eugenol prostaglandin-endoperoxide synthase 2 Homo sapiens
4 Taken together, eugenol might induce COX-2 expression through the activation of NF-kappaB in human osteoblasts. Eugenol prostaglandin-endoperoxide synthase 2 Homo sapiens