Title : Changes in the prodynorphin gene and DARPP-32 state in 6-OHDA-lesioned rats following long-term treatment with l-dopa.

Pub. Date : 2007 Oct 9

PMID : 17884291






2 Functional Relationships(s)
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1 Changes in the prodynorphin gene and DARPP-32 state in 6-OHDA-lesioned rats following long-term treatment with l-dopa. Levodopa protein phosphatase 1, regulatory (inhibitor) subunit 1B Rattus norvegicus
2 Our data demonstrated significantly increased levels of PDyn mRNA and phospho-Thr-34 DARPP-32 and significantly decreased phospho-Thr-75 DARPP-32 in LID rats compared with control and l-dopa treated groups. Levodopa protein phosphatase 1, regulatory (inhibitor) subunit 1B Rattus norvegicus