Pub. Date : 2007 Sep 19
PMID : 17881521
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Whole-cell recordings from mouse enhanced green fluorescent protein-GnRH neurons revealed that the K(ATP) channel opener diazoxide induced an outward current that was antagonized by the sulfonylurea receptor 1 (SUR1) channel blocker tolbutamide. | Diazoxide | ATP-binding cassette, sub-family C (CFTR/MRP), member 8 | Mus musculus |
2 | Whole-cell recordings from mouse enhanced green fluorescent protein-GnRH neurons revealed that the K(ATP) channel opener diazoxide induced an outward current that was antagonized by the sulfonylurea receptor 1 (SUR1) channel blocker tolbutamide. | Diazoxide | ATP-binding cassette, sub-family C (CFTR/MRP), member 8 | Mus musculus |
3 | Single-cell reverse transcription (RT)-PCR revealed that the majority of GnRH neurons expressed Kir6.2 and SUR1 subunits, which correlated with the diazoxide/tolbutamide sensitivity. | Diazoxide | ATP-binding cassette, sub-family C (CFTR/MRP), member 8 | Mus musculus |