Pub. Date : 2007 Jul-Sep
PMID : 17880775
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | An increase in immunoreactivity to nitrotyrosine, iNOS, TNF-alpha and IL-1beta was also observed in the lungs of BLM-treated mice. | Bleomycin | interleukin 1 beta | Mus musculus |
2 | In contrast, administration of BLM-treated mice with TDZD-8 (1 mg/kg daily) significantly reduced (I) the degree of lung injury, (II) the increase in staining (immunohistochemistry) for myeloperoxidase (MPO), nitrotyrosine, iNOS, TNF-alpha and IL-1beta and (III) the degree of apoptosis, as evaluated by Bax and Bcl-2 immunoreactivity and TUNEL staining. | Bleomycin | interleukin 1 beta | Mus musculus |