Title : IFN regulatory factor 8 mediates apoptosis in nonhemopoietic tumor cells via regulation of Fas expression.

Pub. Date : 2007 Oct 1

PMID : 17878376






3 Functional Relationships(s)
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Protein Name
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1 Interestingly, the constitutively expressed IRF8 was also essential for TNF-alpha sensitization of Fas-mediated apoptosis because disruption of IRF8 function also inhibited TNF-alpha-sensitized and Fas-mediated apoptosis. ammonium ferrous sulfate tumor necrosis factor Homo sapiens
2 Interestingly, the constitutively expressed IRF8 was also essential for TNF-alpha sensitization of Fas-mediated apoptosis because disruption of IRF8 function also inhibited TNF-alpha-sensitized and Fas-mediated apoptosis. ammonium ferrous sulfate tumor necrosis factor Homo sapiens
3 Interestingly, the constitutively expressed IRF8 was also essential for TNF-alpha sensitization of Fas-mediated apoptosis because disruption of IRF8 function also inhibited TNF-alpha-sensitized and Fas-mediated apoptosis. ammonium ferrous sulfate tumor necrosis factor Homo sapiens