Pub. Date : 2007
PMID : 17873497
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | BACKGROUND: Interferon-alpha (IFN-alpha) treatment is often associated with psychiatric side effects and has been found to lower the amount of tryptophan (TRP) available to the brain. | Tryptophan | interferon alpha 1 | Homo sapiens |
| 2 | BACKGROUND: Interferon-alpha (IFN-alpha) treatment is often associated with psychiatric side effects and has been found to lower the amount of tryptophan (TRP) available to the brain. | Tryptophan | interferon alpha 1 | Homo sapiens |
| 3 | The alterations in tryptophan metabolism might underlie the psychiatric side effects during treatment with IFN-alpha. | Tryptophan | interferon alpha 1 | Homo sapiens |
| 4 | RESULTS: During treatment with IFN-alpha, several alterations in laboratory parameters occurred that were consistent with an increased degradation of peripheral TRP. | Tryptophan | interferon alpha 1 | Homo sapiens |
| 5 | CONCLUSION: In this study, IFN-alpha was found to alter TRP metabolism without inducing psychiatric side effects. | Tryptophan | interferon alpha 1 | Homo sapiens |