Pub. Date : 2007 Nov 15
PMID : 17853438
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In the present study we used the MPT inhibitor cyclosporine-A (CsA) to preserve mitochondrial NAD(+) pools during PARP-1 activation and thereby provide an estimate of mitochondrial NAD(+) pool size in different cell types. | Cyclosporine | excision repaiross-complementing rodent repair deficiency, complementation group 8 | Mus musculus |
| 2 | Inhibition of the mitochondrial permeability transition with cyclosporine-A (CsA) prevented PARP-1-induced NAD(+) depletion to a varying degree in the four cell types tested. | Cyclosporine | excision repaiross-complementing rodent repair deficiency, complementation group 8 | Mus musculus |