Pub. Date : 2007 Dec
PMID : 17851041
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We hypothesized that the gene PNPO (pyridoxine 5"-phosphatase oxidase gene) might be a candidate for susceptibility to schizophrenia because PNPO encodes pyridoxamine 5"-phosphate oxidase (EC 1.4.3.5), a rate-limiting enzyme in pyridoxal 5"-phosphate (PLP, vitamin B(6)) synthesis. | Niacinamide | pyridoxal phosphatase | Homo sapiens |
| 2 | PLP is a metabolically-active form of vitamin B(6) and thus, is required as a co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. | Niacinamide | pyridoxal phosphatase | Homo sapiens |