Title : Nelfinavir, A lead HIV protease inhibitor, is a broad-spectrum, anticancer agent that induces endoplasmic reticulum stress, autophagy, and apoptosis in vitro and in vivo.

Pub. Date : 2007 Sep 1

PMID : 17785575






1 Functional Relationships(s)
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1 Akt was variably inhibited by HIV protease inhibitors, but nelfinavir caused the greatest inhibition of endogenous and growth factor-induced Akt activation. Nelfinavir AKT serine/threonine kinase 1 Homo sapiens