Title : GEF what? Dock180 and related proteins help Rac to polarize cells in new ways.

Pub. Date : 2007 Aug

PMID : 17765544






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Two distinct families of GEFs for Rho GTPases have been reported so far, based on the features of their catalytic domains: firstly, the classical GEFs, which contain a Dbl homology-pleckstrin homology domain module with GEF activity, and secondly, the Dock180-related GEFs, which contain a Dock homology region-2 domain that catalyzes guanine nucleotide exchange on Rho GTPases. Guanine Nucleotides Rho/Rac guanine nucleotide exchange factor 2 Homo sapiens