Title : Myeloperoxidase inactivates TIMP-1 by oxidizing its N-terminal cysteine residue: an oxidative mechanism for regulating proteolysis during inflammation.

Pub. Date : 2007 Nov 2

PMID : 17726014






1 Functional Relationships(s)
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1 Here, we show that HOCl generated by the MPO-H2O2-chloride system inactivates TIMP-1 by oxidizing its N-terminal cysteine. Chlorides myeloperoxidase Homo sapiens