Title : Transient down-regulation of c-myc protooncogene expression by the alkaloid nicotine in human promyelocytic HL-60 cells.

Pub. Date : 1991 Jun

PMID : 1772432






3 Functional Relationships(s)
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1 Transient down-regulation of c-myc protooncogene expression by the alkaloid nicotine in human promyelocytic HL-60 cells. Nicotine MYC proto-oncogene, bHLH transcription factor Homo sapiens
2 We report herein that the nicotine-induced phenotype change is accompanied by the transient reduced expression of mRNA for the protooncogene c-myc. Nicotine MYC proto-oncogene, bHLH transcription factor Homo sapiens
3 The suppressive effect of nicotine on c-myc mRNA levels is not reversed by the addition of ADP-ribosyl transferase inhibitor, 3-aminobenzamide. Nicotine MYC proto-oncogene, bHLH transcription factor Homo sapiens