Title : The role of electrostatics in colicin nuclease domain translocation into bacterial cells.

Pub. Date : 2007 Oct 26

PMID : 17720814






1 Functional Relationships(s)
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1 We show that cell killing by the DNase toxin colicin E9 of E. coli HDL11, a strain in which the level of anionic phospholipid and hence inner membrane charge is regulated by isopropyl beta-D-thiogalactopyranoside induction, is critically dependent on the level of inducer, whereas this is not the case for pore-forming colicins that take the same basic route into the periplasm. Isopropyl Thiogalactoside colicin E8 Escherichia coli