Title : [Assessment of biotransformation capacity following oral administration of various model substances as cocktail].

Pub. Date : 1991 Dec

PMID : 1771946






1 Functional Relationships(s)
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1 A cocktail of four model substances orally administered to humans is used for simultaneous characterization of phenobarbital and 3-methylcholanthrene inducible forms of cytochrome-P450 and two genetic polymorphisms, the debrisoquine hydroxylation and N-acetylation. Methylcholanthrene cytochrome P450 family 4 subfamily F member 3 Homo sapiens