Title : [The effect of anthocyanins on cholesterol efflux from mouse peritoneal macrophage-derived foam cells and its possible molecular mechanism].

Pub. Date : 2007 Jun

PMID : 17711725






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 ABCA1 expressions at mRNA and protein levels were also significantly enhanced after anthocyanins treatment in these cells and these effects could be blocked by co-treatment with DIDS, an inhibitor of the transport activities of ABCA1 and blocker of apoAI-mediated cholesterol efflux. Anthocyanins ATP-binding cassette, sub-family A (ABC1), member 1 Mus musculus
2 ABCA1 expressions at mRNA and protein levels were also significantly enhanced after anthocyanins treatment in these cells and these effects could be blocked by co-treatment with DIDS, an inhibitor of the transport activities of ABCA1 and blocker of apoAI-mediated cholesterol efflux. Anthocyanins ATP-binding cassette, sub-family A (ABC1), member 1 Mus musculus
3 CONCLUSION: These data demonstrate that anthocyanins induce cholesterol efflux from mouse peritoneal macrophage-derived foam cells via regulating ABCA1 expression. Anthocyanins ATP-binding cassette, sub-family A (ABC1), member 1 Mus musculus