Pub. Date : 2007 Oct 1
PMID : 17707585
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Differential effect of arecoline on the endogenous dioxin-responsive cytochrome P450 1A1 and on a stably transfected dioxin-responsive element-driven reporter in human hepatoma cells. | Arecoline | cytochrome P450 family 1 subfamily A member 1 | Homo sapiens |
| 2 | It was also shown that arecoline, a major areca nut alkaloid, inhibited the 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced cytochrome P450 1A1 (CYP1A1) activation in Huh-7 cells. | Arecoline | cytochrome P450 family 1 subfamily A member 1 | Homo sapiens |
| 3 | It was also shown that arecoline, a major areca nut alkaloid, inhibited the 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced cytochrome P450 1A1 (CYP1A1) activation in Huh-7 cells. | Arecoline | cytochrome P450 family 1 subfamily A member 1 | Homo sapiens |
| 4 | In the present study, the effect of arecoline on the TCDD-induced activation of DRE-CALUX and CYP1A1 enzyme in Huh7-DRE-Luc and Huh-7 cells, respectively, was examined. | Arecoline | cytochrome P450 family 1 subfamily A member 1 | Homo sapiens |
| 5 | It was found that arecoline inhibited TCDD-induced CYP1A1 activation and however enhanced TCDD-induced DRE-CALUX activation. | Arecoline | cytochrome P450 family 1 subfamily A member 1 | Homo sapiens |
| 6 | This finding indicates the differential effect of arecoline on the endogenous dioxin-responsive CYP1A1 and on a stably transfected DRE-driven reporter in human hepatoma cells. | Arecoline | cytochrome P450 family 1 subfamily A member 1 | Homo sapiens |