Title : Differential regulation of endothelial cell permeability by cGMP via phosphodiesterases 2 and 3.

Pub. Date : 2007 Oct 12

PMID : 17704206






1 Functional Relationships(s)
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1 When cAMP synthesis was slightly elevated with a submaximal concentration of 7-deacetyl-7-(O-[N-methylpiperazino]-gamma-butyryl)-dihydrochloride-forskolin (MPB-forskolin), we found that low doses of either atrial natriuretic peptide (ANP) or NO donors potentiated the inhibitory effects of MPB-forskolin on thrombin-induced permeability. Colforsin coagulation factor II, thrombin Homo sapiens