Title : Human T-cell leukemia virus type 1 Tax oncoprotein prevents DNA damage-induced chromatin egress of hyperphosphorylated Chk2.

Pub. Date : 2007 Oct 5

PMID : 17698850






6 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Analysis of chromatin-bound Chk2 from Tax-expressing cells revealed phosphorylation at Thr(378), Ser(379), Thr(383), Thr(387), and Thr(389). Threonine checkpoint kinase 2 Homo sapiens
2 Analysis of chromatin-bound Chk2 from Tax-expressing cells revealed phosphorylation at Thr(378), Ser(379), Thr(383), Thr(387), and Thr(389). Threonine checkpoint kinase 2 Homo sapiens
3 Analysis of chromatin-bound Chk2 from Tax-expressing cells revealed phosphorylation at Thr(378), Ser(379), Thr(383), Thr(387), and Thr(389). Threonine checkpoint kinase 2 Homo sapiens
4 Analysis of chromatin-bound Chk2 from Tax-expressing cells revealed phosphorylation at Thr(378), Ser(379), Thr(383), Thr(387), and Thr(389). Threonine checkpoint kinase 2 Homo sapiens
5 In contrast, chromatin-bound Chk2 in the absence of Tax was phosphorylated at Thr(383) and Thr(387) in response to ionizing radiation. Threonine checkpoint kinase 2 Homo sapiens
6 In contrast, chromatin-bound Chk2 in the absence of Tax was phosphorylated at Thr(383) and Thr(387) in response to ionizing radiation. Threonine checkpoint kinase 2 Homo sapiens