Title : 5HT1F- and 5HT7-receptor agonists for the treatment of migraines.

Pub. Date : 2007 Aug

PMID : 17691977






1 Functional Relationships(s)
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1 Serotonin was the first neurotransmitter believed to be involved in cephalic pain transfer forward to the cortex, but the precise mechanism was confirmed only after sumatriptan, a 5-HT(1B/1D0) high affinity agonist, was introduced in the acute treatment of migraine. Serotonin 5-hydroxytryptamine receptor 1B Homo sapiens