Title : LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake.

Pub. Date : 2007 Sep 7

PMID : 17690258






1 Functional Relationships(s)
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1 We determined the crystal structure at 2.9 angstroms of the bacterial leucine transporter (LeuT), a homolog of SERT, NET, and DAT, in complex with leucine and the antidepressant desipramine. Leucine solute carrier family 6 member 3 Homo sapiens