Title : Cloning and characterization of two human VIP1-like inositol hexakisphosphate and diphosphoinositol pentakisphosphate kinases.

Pub. Date : 2007 Oct 19

PMID : 17690096






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Cloning and characterization of two human VIP1-like inositol hexakisphosphate and diphosphoinositol pentakisphosphate kinases. Phytic Acid diphosphoinositol pentakisphosphate kinase 1 Homo sapiens
2 Recombinant human VIP1 exhibits in vitro IP6 and IP7 kinase activities and restores IP7 synthesis when expressed in mutant yeast. Phytic Acid diphosphoinositol pentakisphosphate kinase 1 Homo sapiens
3 Our data demonstrate that human VIP1 and VIP2 function as IP6 and IP7 kinases that act along with the IP6K/Kcs1-class of kinases to convert IP6 to IP8 in mammalian cells, a process that has been found to occur in response to various stimuli and signaling events. Phytic Acid diphosphoinositol pentakisphosphate kinase 1 Homo sapiens