Title : DGA1 (diacylglycerol acyltransferase gene) overexpression and leucine biosynthesis significantly increase lipid accumulation in the Deltasnf2 disruptant of Saccharomyces cerevisiae.

Pub. Date : 2007 Nov 15

PMID : 17688423






1 Functional Relationships(s)
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1 The effect of LEU2 expression on growth and lipid accumulation could be reproduced by adding large amounts of leucine to the culture medium, indicating that the effect was not due to Leu2p (beta-isopropylmalate dehydrogenase) itself, but rather to leucine biosynthesis. Leucine 3-isopropylmalate dehydrogenase Saccharomyces cerevisiae S288C